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หมวดหมู่ : 3. Protein & Enzyme ,  Recombinant protein ,  Servicebio , 
แบรนด์ : Servicebio
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DESCRIPTION | ||
Gene Name Synonym | IL-7, IL7, Interleukin-7 | |
Species | Human | |
Accession | P13232 | |
Source | HEK293 Cells | |
SPECIFICATIONS | ||
Amino acid sequence | Met1-His117 is expressed with a 10×His tag at the C terminus | |
Molecular Weight | 21.6 kDa | |
Purity | >95.0% as determined by SDS-PAGE | |
Endotoxin | <5 EU·mg-1 | |
Formulation | Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. | |
Reconstitution | Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. | |
STORAGE | ||
Stability and Storage | 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. | |
BACKGROUND | ||
Interleukin-7 (IL-7) was discovered in 1980s. It is one of the members of IL-2 superfamily. IL-7 is a cytokine that has been known since long in immunology, mainly regarding its effects on T-cells and B-cells. IL-7 has been demonstrated to be necessary for both B-cell and T-cell proliferation and lack of IL-7 causes immature immune cell arrest. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL-7 plays in aging may permit parsimonious preventative or therapeutic solutions for diverse conditions. | ||
Data | ||
SDS-PAGE | Bioactivity | |
| Testing in progress | |
Recombinant Human IL-7 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 20-30 kDa. |
For Research Use Only!
Ver. No.: V1.0-202102