(-)-Nicotine hydrogen tartrate salt

Synonyms: (−)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt; Nicotine bitartrate dihydrate; Nicotine ditartrate dihydrate; Nicotine powder; Nicotine tartrate

Nicotine is a naturally derived alkaloid found in the nightshade family of plants. It is a toxic, highly addictive central nervous system stimulant. Nicotine hydrogen tartrate salt is more stable during storage than the base form.
Note: Tested according to ISO 13276

Product Detail

Glentham Code : GL9693
Product Categories : APIs   Biochemicals   Phytochemicals   Alkaloids  
CAS R : 65-31-6
Alternative CAS RNs : 6019-06-3 (·2H2O), 2624-48-8, 54-11-5 (base)
EC Number : 200-607-2
MDL Number : MFCD00069368
PubChem Substance ID : 295369473
Storage Temperature : +4°C
Shipping Temperature : Ambient
Harmonised Tariff Code : 2939791000

Product Specification

Physical Description : White to almost white powder
Solubility :

• 10% in water: Soluble 
  
• 1% in 96% ethanol: Slightly soluble
  

Identification : IR
pH (10% in water) : 3.0 - 3.4
Specific Optical Rotation : +21.0 - +23.0 ° (1% in water)
Related Substances (HPLC) : 

• Any Specified Impurity: ≤ 0.3%
  
• (Continine, Myosmine, Nicotine-N-oxide, beta-Nicotyrine, Anatabine, Anabasine, Nornicotine)
  
• Unspecified Impurity: ≤ 0.1%
  
• Total Impurities: ≤ 0.8%
  

Water : 6.9 - 8.0 %
Sulphated Ash : ≤ 0.1%
Assay (HPLC) : 98.5 - 101.5 % (anhydrous basis)
Residual Solvents : Ethanol: ≤ 5000ppm, Methanol: ≤ 3000ppm
Pharmacopoeia Specification(s) : EP
Specification Version : 1.1

Signal word : Danger

Hazard statements

• H300: Fatal if swallowed.
  
• H310: Fatal in contact with skin.
  
• H330: Fatal if inhaled.
  
• H411: Toxic to aquatic life with long lasting effects.

Precautionary statements

• P260: Do not breathe dust/fume/gas/mist/vapours/spray.
  
• P273: Avoid release to the environment.
  
• P280: Wear protective gloves/protective clothing/eye protection/face protection.
  
• P284: Wear respiratory protection.
  
• P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
  
• P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
  
• P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
  
• P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  
• P310: Immediately call a POISON CENTER or doctor/physician.

UN Number : UN1659 - 6.1 - PG II

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